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Автор: Vaneet Dhir and Pooja Dhand
Год: 2011
Издание:
LAP Lambert Academic Publishing
Страниц: 64
ISBN: 9783846593493
This approach was made by Dhir et al. based on X-ray Crystallography in terms of Toxicity versus Proximity on the basis of Ligand preparation and characterization by Nuclear Magnetic Spectroscopy, Infra red spectroscopy, Magnetic Susceptibility & CHN(Mass Analyzer) Techniques. DETP & DPTP have been found to be similar potential toxic as they have been used in fungicides and other antibacterial products. Approach has been made on the basis of Biomimetics. The study reveals that Cu complexes are much more potentially toxic than lead compounds because in lead compounds ligands may occupy all the centres or corners of the Pb(I/II)metal ions and very less void is left to interact physiochemically with various proteins/ amino acids or DNA of living cell to disrupt their cycle to become potential toxic and carcinogenic in nature. Thus Pb(I/II)metal ions are very toxic with less hydrophobic group while Cu(II) complexes are very toxic with big/steric ligands as compared to small one. This fact...
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![Источник: 2o Visconde de Vila Maior, O Douro illustrado: album do rio Douro e paiz vinhateiro album de ce fleuve et de son pays vignoble / an album of the river Douro and adjacent wine ... the Original from 1876] (Portuguese Edition)](http://www.ozon.ru/multimedia/books_covers/1005734541.jpg)