Small Molecule Inhibitors of the SARS-CoV Nsp15: Mechanism of Action and Insight Into Coronavirus Infection
Автор:Joanna Ortiz-Alcantara Год: 2012 Издание: [не указанo] Страниц: 68 ISBN: 3848407639 The Severe Acute Respiratory Syndrome (SARS) virus encodes several unusual RNA processing enzymes, including Nsp15, an endoribonuclease that cleaves 3a?? of uridylates through a Ribonuclease A-like mechanism. Crystal structures confirmed that the Nsp15 ac