RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay, Volume 448 (Methods in Enzymology) (Methods in Enzymology)
Автор: [автор не указан] Год: 2008 Издание:
Страниц: 656 ISBN: 0123743788 Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements, responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. The control of biological processes, such as cellular growth and differentiation, is dependent on how the genetic material within a cell is expressed. The cellular physiology of mRNAincluding mRNA processing, transport, localization, and turnoveris central to the process of gene expression.Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway. Expert researchers introduce the most...
