QSAR of pyrimidinediones & their comparison with Rosiglitazone
Автор:Prashant Singh Год: 2012 Издание:LAP Lambert Academic Publishing Страниц: 116 ISBN: 9783659167096 Through physico-chemical studies, we screened some of the compounds 1-215 and few of them showed comparable QSAR properties to standard drug rosiglitazone (clinical trials). After studying their computational biological properties, only two compounds are the most prominent and can be used to cure diabetes after their synthesis. Thus, computational studies save the times as well as chemical consumption.
