Partition Equilibrium And Lipophilicity Of Hydroxamic Acids
Автор:Rama Pande,Deepesh Khare and Priyanka Singh Год: 2013 Издание:LAP Lambert Academic Publishing Страниц: 92 ISBN: 9783659430350 N-Arylhydroxamic acids are drug like molecules. Biological activity always depends upon physico-chemical property namely lipophilicity, which has direct impact on the potency of the molecule. Partition coefficient is a measure of how well a substance partitions between a lipid and water.The partition coefficient has a strong influence on ADME properties of molecules. Both of these parameters are important factor in QSAR.
