DCE-MRI: lesion detection and classification in Breast Cancer
Автор:Roberta Fusco,Mario Sansone and Antonella Petrillo Год: 2013 Издание:LAP Lambert Academic Publishing Страниц: 160 ISBN: 9783659427572 Dynamic contrast-enhanced MRI (DCE-MRI) is a well established, high-performance, imaging modality for the diagnosis and management of patients with solid tumors. In the last two decades, the diagnosis, grading and classification of tumours has considerably benefited from the development of DCE-MRI which is now essential for the adequate clinical management of many tumour types. The main aim of this work is to investigate the use of semi-quantitative and quantitative functional parameters for segmentation and classification of breast lesions via DCE-MRI. The objectives of the work can be detailed as follows: to review and describe the most diffused techniques for evaluating the time intensity curve in DCE-MRI with a focus on tracer kinetics models proposed in literature; to evaluate the influence of the parametrization of the classic bi-compartmental model; to assess the performance of simultaneous tracer kinetic modelling and pixel classification as either suspicious...
