Общая и неорганическая химия

Список источников >Нехудожественная литература >Научная и техническая литература >Естественные науки >Химические науки >Общая и неорганическая химия >

Biological evaluation of some 2,5-disubstituted-1,3,4-oxadiazoles

Автор: Dinesh Mehta and Rina Das
Год: 2011
Издание: LAP Lambert Academic Publishing
Страниц: 60
ISBN: 9783846553572
2-5-disubstituted 1,3,4-oxadiazoles constitute a unique class of nitrogen and oxygen containing 5-membered hetero cycles. During the past years considerable evidence also accumulate to demonstrate the efficacy of 1,3,4-oxadiazoles including anti-malarial, anti-bacterial, anti-inflammatory and other biological activities. In an attempt for the enhancement of biological activity incorporation of 1,3,4-oxadiazoles was made with furan moiety. The main objective was to synthesize various 2,5-disubstituted-1,3,4-oxadiazoles, which were characterized by different spectroscopic techniques (IR,NMR,MASS). Analysis of spectral data of all the compounds revealed the successful formation of Different derivatives derived from 2,5-disubstituted-1,3,4-oxadiazoles and antibacterial and anti-inflammatory activities were evaluated.

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