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Автор: Jesse Russell
Год: 2013
Издание:
Книга по Требованию
Страниц: 100
ISBN: 9785508217952
High Quality Content by WIKIPEDIA articles! Microcephalin (MCPH1) is one of six genes causing primary microcephaly (Online 'Mendelian Inheritance in Man' (OMIM) 251200) when non-functional mutations exist in the homozygous state. Derived from the Greek words for "small" and "head", this condition is characterised by a severely diminished brain. Hence it has been assumed that variants have a role in brain development, but in normal individuals no effect on mental ability or behavior has yet been demonstrated in either this or another similarly studied microcephaly gene, ASPM. However, an association has been established between normal variation in brain structure as measured with MRI (i.e., primarily cortical surface area and total brain volume) and common genetic variants within both the MCPH1 gene and another similarly studied microcephaly gene, CDK5RAP2. Данное издание представляет собой компиляцию сведений, находящихся в свободном доступе в среде Интернет в целом, и в...
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