Interferon-Gamma: A marker of tuberculosis mediated immune response
Автор:Shahid Hussain and Nadeem Afzal Год: 2013 Издание:LAP Lambert Academic Publishing Страниц: 72 ISBN: 9783659372407 Background: Interferon gamma (IFN-?), a cytokine produced by a variety of cells is involved in the immune response against M.tuberculosis. It activates the production of other cytokines & molecules that kill MTB. IFN-? also has diagnostic role in identification of active and latent TB. Objective: To determine the level of IFN-? in the blood of TB patients. Methods: 91 subjects were selected, including 54 active TB patients and 37 healthy controls. IFN-? conc. was determined in their blood by ELISA technique. Results: In TB patients, Mean+SD of IFN-? was 48.69+28.78 while it was 12.99+5.70 pg/ml in control group (p ...
