Effect Of Acrylamide On Male and Female Albino Rats
Автор:Sohair R. Fahmy,Sayed M. Rawi and Mohamed-Assem. S. Marie Год: 2013 Издание:LAP Lambert Academic Publishing Страниц: 264 ISBN: 9783659394607 Acrylamide (ACR) is neurotoxic to experimental animals and humans. The literature on its neurotoxic effect in the mature animals is huge, but the effect of acrylamide on the immature is relatively less understood. The present study was carried out to investigate the hematological, biochemical, neurological and histopathological effects of acrylamide (15 mg/kg b.wt.) in immature and mature male and female rats as well as mature male and female rats at (50 mg/kg b. wt.). As could be shown histopathological alteration in the structures of treated liver, kidney, brain, testis and ovary which resulted following ACR administration. In conclusion, the present study showed that, acrylamide induced hematological, biochemical, neurological and histopathological disorders in the immature and mature male and female rats. So, we recommended that it must be eat a balanced diet, rich in fruits and vegetables and avoid fast or junk foods. Key
