Академическая литература издательств Америки

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Protein-Protein Interactions as New Drug Targets (Handbook of Experimental Pharmacology)

Автор: [автор не указан]
Год: 2008
Издание: [не указанo]
Страниц: 512
ISBN: 3540728422
Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interacions are likely to act with fewer side effects than conventional medication influencing whole cell functions. This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transducton processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted.
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